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About Us

ACHIEVING MORe FOR RNA TREATMENTs

Our Story

Guided by our team of srRNA experts and with a customizable library of synthetic srRNA vectors and end-to-end development capabilities at our disposal, we are uniquely positioned to develop safe and effective srRNA immunotherapies that maximize impact for more patients.
Our story began in 2014
Replicate co-founders Nathaniel Wang, Ph.D. and Andy Geall, Ph.D. had spent years working together in RNA vaccine development.
An idea for a vector-driven platform
They started Replicate to answer the question, “If we wanted to create the best self-replicating RNA platform from scratch, how would we do it?”
Broadening applications
Joining with former colleagues Herbert Kim Lyerly, M.D., and Zachary Hartman, Ph.D., professors of cancer research and immunology at Duke University, the founding team began to explore preventing or removing drug-resistant cancer mutations using srRNA.
The work begins
Replicate exclusively licensed from Duke technology to prevent drug-resistant cancer mutations. Then we got to work building new vectors from scratch.
Today
We have since made rapid progress in identifying many promising srRNA preclinical candidates in infectious disease, oncology, and autoimmune diseases.
Learn more about our
srRNA platform
OUR SCIENCe
A strand of srRNA floats upwards to the right. Behind it, copied mRNA segments are visible. The background is teal and a white, curved light trail follows the path of the srRNA. A strand of srRNA floats upwards to the right. Behind it, copied mRNA segments are visible. The background is teal and a white, curved light trail follows the path of the srRNA.
A Replicate employee presents in front of a large screen of data. A Replicate employee presents in front of a large screen of data.
A scientist wearing lab goggles and black gloves holds a tray of pipetted liquid. A scientist wearing lab goggles and black gloves holds a tray of pipetted liquid.
Four Replicate employees smile and converse around a table. Four Replicate employees smile and converse around a table.
Our Team
The Replicate Team
The Replicate Team Board of Directors Scientific Advisory Board
Headshot of Nathaniel Wang in a light blue circular frame. Nathaniel Wang, PhD Chief Executive Officer and Co-Founder View Bio
Headshot of Andrew Geall in a light blue circular frame. Andrew Geall, PhD Chief Development Officer and Co-Founder View Bio
Headshot of Parinaz Aliahmad in a light blue circular frame. Parinaz Aliahmad, PhD Chief Scientific Officer View Bio
Headshot of Terrina Bayone in a light blue circular frame. Terrina Bayone
Headshot of Emily Brand in a light blue circular frame. Emily Brand
Headshot of Michael Brown in a light blue circular frame. Michael Brown
A simple blue line-drawing pattern of three dark blue human silhouettes on a light blue circular frame. Jose Cardona
Headshot of Christine Domingo in a light blue circular frame. Christine Domingo
Headshot of Jasmin Gonzalez in a light blue circular frame. Jasmin Gonzalez
Headshot of Thomas Goodman in a light blue circular frame. Thomas Goodman
Headshot of Hunter Little in a light blue circular frame. Hunter Little
Headshot of Christian Maine in a light blue circular frame. Christian Maine
Headshot of Shigeki Miyake-Stoner in a light blue circular frame. Shigeki Miyake-Stoner
Headshot of Melanie Olesiuk in a light blue circular frame. Melanie Olesiuk
Headshot of Gaelle Picarda in a light blue circular frame. Gaelle Picarda
Headshot of Jacqueline Posy in a light blue circular frame. Jacqueline Posy
Headshot of Jessica Sparks in a light blue circular frame. Jessica Sparks
Headshot of Darina Spasova in a light blue circular frame. Darina Spasova
Headshot of Laura Vegar in a light blue circular frame. Laura Vegar
Michael Ehlers, MD, PhD Chair and Co-Founder View Bio
Nathaniel Wang, PhD View Bio
Seth L. Harrison, MD View Bio
Joseph A. Yanchik III View Bio
Anna Blakney, PhD View Bio
Herbert Kim Lyerly, MD Co-Founder View Bio
Zachary Hartman, PhD Co-Founder View Bio
Philip Santangelo, PhD View Bio
Jeffrey Ulmer, PhD View Bio
Want to be a part of the next revolution in RNA therapeutics?
JOIN Us
A cut-out image of a scientist wearing lab goggles, black gloves, and a white lab coat inspecting a tube of orange liquid, superimposed over a light blue wave background with a white light trail. A cut-out image of a scientist wearing lab goggles, black gloves, and a white lab coat inspecting a tube of orange liquid, superimposed over a light blue wave background with a white light trail.